| Children |
| | 1. John Preston, b. 1708, ., Killingly, Windham, Connecticut d. 11 Mar 1740 (Age 32 years) |
| | 2. Mary Preston, b. 1709, ., Killingly, Windham, Connecticut d. 13 Apr 1766 (Age 57 years) |
| | 3. Susannah Preston, b. 9 Sep 1711, ., Killingly, Windham, Connecticut d. 24 Apr 1788 (Age 76 years) |
| | 4. Jonathan Preston, b. Feb 1714, ., Killingly, Windham, Connecticut  |
| | 5. Joseph Preston, b. 28 Feb 1717, ., Killingly, Windham, Connecticut  |
| | 6. Benjamin Preston, b. 22 Jun 1718, ., Killingly, Windham, Connecticut  |
| | 7. Theodore Preston, b. 1720, ., Killingly, Windham, Connecticut  |
| | 8. William Preston, b. 1721, ., Killingly, Windham, Connecticut d. 1776 (Age 55 years) |
| | 9. Abigail Preston, b. 1723, , Suffolk, Massachusetts, British Colonial America d. 10 May 1814, Randolph, Orange, Vermont, United States (Age 91 years) |
| | 10. David Preston, b. 10 Oct 1725, ., Killingly, Windham, Connecticut  |
| | 11. Samuel Preston, b. 20 Aug 1727, ., Killingly, Windham, Connecticut  |
| | 12. Sarah Preston, b. 6 Feb 1729/1730, ., Windham, Windham, Connecticut d. 18 Mar 1730/1731, ., Windham, Windham, Connecticut (Age 1 year) |
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